Casper is a friendly ghost--the friendliest ghost you know! Unfortunately he lives with his three Hauntaholic uncles: Uncle Stretch, who's convinced he's smarter than anyone who ever died; Stinkie, who can put down any fleshie with one belch-blast; and Fatso, who's big, round and not too bright. Trying to cure these brothers is Dr. James Harvey and his spunky and worldly daughter Kat. Put them all under one roof and you have a house full of fun.

• Malachi Pearson
• Joe Nipote
• Joe Alaskey
• Jess Harnell
• Dan Castellaneta
• Kath Soucie
• Rob Paulsen
• Miriam Flynn