Newly widowed Helen Blacke inherits the Blacke Foundation, a scientific research institute located in the Highcliffe Manor on an island off the Massachusetts coast and populated by mad scientists who want to get rid of her.

• Shelley Fabares
• Stephen McHattie
• Eugenie Ross-Leming
• Gerald Gordon
• Audrey Landers
• Jenny O'Hara
• Chris Marlowe
• David Byrd