Cosmic Era 71. Mankind has developed into two subspecies: Naturals, who reside on Earth, and Coordinators, genetically enhanced humans capable of withstanding the rigors of space who inhabit orbital colonies known as PLANTs. The story revolves around a young Coordinator named Kira Yamato, who becomes involved in the war between the two races after a neutral space colony secretly developing mobile suits for the Earth Alliance is attacked by the PLANTs' military force, ZAFT.

• Kenichi Suzumura
• Maaya Sakamoto
• Toshihiko Seki
• Fumiko Orikasa
• Mami Koyama
• Hiroki Takahashi
• Akira Ishida
• Soichiro Hoshi