After breaking up with her girlfriend, a nightclub singer, Jane, answers a personal ad from Robin, a real estate agent with AIDS, seeking a cross-country travel partner. On their journey from New York City to Los Angeles, the two stop by Pittsburgh to pick up Jane's friend Holly, who is trying to escape an abusive relationship. With three distinct personalities, the women must overcome their differences to help one another.

• Regency Enterprises
• Alcor Films
• Whoopi Goldberg
• Mary-Louise Parker
• Drew Barrymore
• Matthew McConaughey
• James Remar
• Billy Wirth
• Jude Ciccolella
• Dennis Boutsikaris