A pampered Beverly Hills chihuahua named Chloe who, while on vacation in Mexico with her owner Viv's niece, Rachel, gets lost and must rely on her friends to help her get back home before she is caught by a dognapper who wants to ransom her.

• Walt Disney Pictures
• Smart Entertainment
• Drew Barrymore
• Piper Perabo
• Andy García
• George Lopez
• Paul Rodríguez
• Plácido Domingo
• Edward James Olmos
• Loretta Devine